• Target：
• PBF

• Gene Name：
• PTTG1IP

• Protein Name：
• Pituitary tumor-transforming gene 1 protein-interacting protein

• Human Gene Id：
• 754

• Human Swiss Prot No：
• P53801

• Mouse Gene Id：
• 108705

• Mouse Swiss Prot No：
• Q8R143

• Rat Gene Id：
• 365548

• Rat Swiss Prot No：
• Q6P767

• Immunogen：
• The antiserum was produced against synthesized peptide derived from human PTTG. AA range:116-165

• Specificity：
• PBF Polyclonal Antibody detects endogenous levels of PBF protein.

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Other Name：
• PTTG1IP;C21orf1;C21orf3;Pituitary tumor-transforming gene 1 protein-interacting protein;Pituitary tumor-transforming gene protein-binding factor;PBF;PTTG-binding factor

• Observed Band(KD)：
• 20kD

• Background：
• This gene encodes a single-pass type I integral membrane protein, which binds to pituitary tumor-transforming 1 protein (PTTG1), and facilitates translocation of PTTG1 into the nucleus. Coexpression of this protein and PTTG1 induces transcriptional activation of basic fibroblast growth factor. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Nov 2013],

• Function：
• function:May facilitate PTTG1 nuclear translocation.,induction:By transcription factor RUNX2.,subcellular location:According to PubMed:10781616 it is found in the cytoplasm and the nucleus.,subunit:Interacts with PTTG1.,tissue specificity:Ubiquitous.,

• Subcellular Location：
• Membrane ; Single-pass type I membrane protein . Cytoplasm . Nucleus . According to PubMed:10781616, it is found in the cytoplasm and the nucleus.

• Expression：
• Ubiquitous.

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