• Target：
• Ran BP-17

• Fields：
• >>Nucleocytoplasmic transport

• Gene Name：
• RANBP17

• Protein Name：
• Ran-binding protein 17

• Human Gene Id：
• 64901

• Human Swiss Prot No：
• Q9H2T7

• Mouse Gene Id：
• 66011

• Mouse Swiss Prot No：
• Q99NF8

• Immunogen：
• The antiserum was produced against synthesized peptide derived from human RANBP17. AA range:145-194

• Specificity：
• Ran BP-17 Polyclonal Antibody detects endogenous levels of Ran BP-17 protein.

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• WB 1:500-2000;IHC 1:50-300

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Other Name：
• RANBP17;Ran-binding protein 17

• Observed Band(KD)：
• 125kD

• Background：
• RAN binding protein 17(RANBP17) Homo sapiens The transport of protein and large RNAs through the nuclear pore complexes (NPC) is an energy-dependent and regulated process. The import of proteins with a nuclear localization signal (NLS) is accomplished by recognition of one or more clusters of basic amino acids by the importin-alpha/beta complex; see MIM 600685 and MIM 602738. The small GTPase RAN (MIM 601179) plays a key role in NLS-dependent protein import. RAN-binding protein-17 is a member of the importin-beta superfamily of nuclear transport receptors.[supplied by OMIM, Jul 2002],

• Function：
• function:May function as a nuclear transport receptor.,similarity:Belongs to the exportin family.,subunit:Binds to nucleoporins and the GTP-bound form of Ran.,tissue specificity:Highly expressed in testis, moderately in pancreas and weakly in other tissues studied.,

• Subcellular Location：
• Cytoplasm . Nucleus . Nucleus, nuclear pore complex .

• Expression：
• Highly expressed in testis, moderately in pancreas and weakly in other tissues studied.

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