Rho H Polyclonal Antibody

    • Catalog No.:YT4083
    • Applications:WB,IHC-p,IF,ELISA
    • Reactivity:Human,Mouse,Rat
      • Gene Name:
      • RhoH
      • Protein Name:
      • Rho-related GTP-binding protein RhoH
      • Human Gene Id:
      • 399
      • Human Swiss Prot No:
      • Q15669
      • Mouse Swiss Prot No:
      • Q9D3G9
      • Immunogen:
      • The antiserum was produced against synthesized peptide derived from human RhoH. AA range:141-190
      • Specificity:
      • Rho H Polyclonal Antibody detects endogenous levels of Rho H protein.
      • Formulation:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • Source:
      • Rabbit
      • Dilution:
      • Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.
      • Purification:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • Concentration:
      • 1 mg/ml
      • Storage Stability:
      • -20°C/1 year
      • Other Name:
      • RHOH; ARHH; TTF; Rho-related GTP-binding protein RhoH; GTP-binding protein TTF; Translocation three four protein
      • MolecularWeight(Da):
      • 21331
      • Observed Band(KD):
      • 21
      • Background:
      • ras homolog family member H(RHOH) Homo sapiens The protein encoded by this gene is a member of the Ras superfamily of guanosine triphosphate (GTP)-metabolizing enzymes. The encoded protein is expressed in hematopoietic cells, where it functions as a negative regulator of cell growth and survival. This gene may be hypermutated or misexpressed in leukemias and lymphomas. Chromosomal translocations in non-Hodgkin's lymphoma occur between this locus and B-cell CLL/lymphoma 6 (BCL6) on chromosome 3, leading to the production of fusion transcripts. Alternative splicing in the 5' untranslated region results in multiple transcript variants that encode the same protein. [provided by RefSeq, May 2013],
      • Function:
      • disease:A chromosomal aberration involving RHOH is found in a non-Hodgkin lymphoma cell line. Translocation t(3;4)(q27;p11) with BCL6.,similarity:Belongs to the small GTPase superfamily. Rho family.,tissue specificity:Transcribed only in hemopoietic cells.,
      • Subcellular Location:
      • immunological synapse,intracellular,cytoplasm,cytosol,plasma membrane,
      • Expression:
      • B-cell,
      • Products Images
      • Immunofluorescence analysis of A549 cells, using RhoH Antibody. The picture on the right is blocked with the synthesized peptide.
      • Western blot analysis of lysates from HT-29 cells, using RhoH Antibody. The lane on the right is blocked with the synthesized peptide.
      • Western blot analysis of the lysates from RAW264.7cells using RhoH antibody.