SENP7 Polyclonal Antibody

    • Catalog No.:YT4241
    • Applications:WB;IHC;IF;ELISA
    • Reactivity:Human;Mouse
      • Target:
      • SENP7
      • Gene Name:
      • SENP7
      • Protein Name:
      • Sentrin-specific protease 7
      • Human Swiss Prot No:
      • Q9BQF6
      • Mouse Swiss Prot No:
      • Q8BUH8
      • Immunogen:
      • The antiserum was produced against synthesized peptide derived from human SENP7. AA range:991-1040
      • Specificity:
      • SENP7 Polyclonal Antibody detects endogenous levels of SENP7 protein.
      • Formulation:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • Source:
      • Polyclonal, Rabbit,IgG
      • Dilution:
      • WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200
      • Purification:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • Concentration:
      • 1 mg/ml
      • Storage Stability:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • Other Name:
      • SENP7;KIAA1707;SSP2;SUSP2;Sentrin-specific protease 7;SUMO-1-specific protease 2;Sentrin/SUMO-specific protease SENP7
      • Observed Band(KD):
      • 112kD
      • Background:
      • The reversible posttranslational modification of proteins by the addition of small ubiquitin-like SUMO proteins (see SUMO1; MIM 601912) is required for many cellular processes. SUMO-specific proteases, such as SENP7, process SUMO precursors to generate a C-terminal diglycine motif required for the conjugation reaction. They also display isopeptidase activity for deconjugation of SUMO-conjugated substrates (Lima and Reverter, 2008 [PubMed 18799455]).[supplied by OMIM, Jun 2009],
      • Function:
      • alternative products:Experimental confirmation may be lacking for some isoforms,caution:The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.,function:Protease that deconjugates SUMO2 and SUMO3 from targeted proteins, but not SUMO1. Catalyzes the deconjugation of poly-SUMO2 and poly-SUMO3 chains. Has very low efficiency in processing full-length SUMO proteins to their mature forms.,similarity:Belongs to the peptidase C48 family.,
      • Subcellular Location:
      • Cytoplasm .
      • Expression:
      • Brain,Epithelium,Fetal kidney,Placenta,
      • Products Images
      • Western Blot analysis of various cells using SENP7 Polyclonal Antibody cells nucleus extracted by Minute TM Cytoplasmic and Nuclear Fractionation kit (SC-003,Inventbiotech,MN,USA).
      • Immunohistochemistry analysis of paraffin-embedded human brain tissue, using SENP7 Antibody. The picture on the right is blocked with the synthesized peptide.
      • Western blot analysis of lysates from HUVEC cells, using SENP7 Antibody. The lane on the right is blocked with the synthesized peptide.