• Target：
• SLC43A1

• Gene Name：
• SLC43A1

• Protein Name：
• Large neutral amino acids transporter small subunit 3

• Human Gene Id：
• 8501

• Human Swiss Prot No：
• O75387

• Mouse Swiss Prot No：
• Q8BSM7

• Immunogen：
• The antiserum was produced against synthesized peptide derived from human LAT3. AA range:231-280

• Specificity：
• SLC43A1 Polyclonal Antibody detects endogenous levels of SLC43A1 protein.

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• WB 1:500-2000;IHC 1:50-300; ELISA 2000-20000

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Other Name：
• SLC43A1;LAT3;PB39;POV1;Large neutral amino acids transporter small subunit 3;L-type amino acid transporter 3;Prostate cancer overexpressed gene 1 protein;Solute carrier family 43 member 1

• Observed Band(KD)：
• 61kD

• Background：
• SLC43A1 belongs to the system L family of plasma membrane carrier proteins that transports large neutral amino acids (Babu et al., 2003 [PubMed 12930836]).[supplied by OMIM, Mar 2008],

• Function：
• function:Sodium-independent, high affinity transport of large neutral amino acids. Has narrower substrate selectivity compared to SLC7A5 and SLC7A8 and mainly transports branched-chain amino acids and phenylalanine. Plays a role in the development of human prostate cancer, from prostatic intraepithelial neoplasia to invasive prostate cancer.,miscellaneous:Up-regulated in early prostate cancer development with highest expression level in seminomas of testicular germ cell tumors.,similarity:Belongs to the SLC43A transporter (TC 2.A.1.44) family.,tissue specificity:In adults, found in all tissues examined with highest expression in pancreas. In fetus, highest expression in liver and lower levels in kidney, and lung. High levels found in prostate cancer cells.,

• Subcellular Location：
• Membrane ; Multi-pass membrane protein .

• Expression：
• In adults, found in all tissues examined with highest expression in pancreas. In fetus, highest expression in liver and lower levels in kidney, and lung. High levels found in prostate cancer cells.

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