TDE1 Polyclonal Antibody

    • Catalog No.:YT4591
    • Applications:WB;IHC;IF;ELISA
    • Reactivity:Human;Mouse;Rat
      • Target:
      • TDE1
      • Fields:
      • >>Viral life cycle - HIV-1
      • Gene Name:
      • SERINC3
      • Protein Name:
      • Serine incorporator 3
      • Human Swiss Prot No:
      • Q13530
      • Mouse Swiss Prot No:
      • Q9QZI9
      • Immunogen:
      • The antiserum was produced against synthesized peptide derived from human SERC3. AA range:361-410
      • Specificity:
      • TDE1 Polyclonal Antibody detects endogenous levels of TDE1 protein.
      • Formulation:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • Source:
      • Polyclonal, Rabbit,IgG
      • Dilution:
      • WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.
      • Purification:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • Concentration:
      • 1 mg/ml
      • Storage Stability:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • Other Name:
      • SERINC3;DIFF33;TDE1;SBBI99;Serine incorporator 3;Tumor differentially expressed protein 1
      • Observed Band(KD):
      • 52kD
      • Background:
      • function:May be involved in cellular transformation.,PTM:N-glycosylated.,similarity:Belongs to the TDE1 family.,tissue specificity:Ubiquitous. Expression levels were increased fourfold to tenfold in lung tumor tissues compared with normal pulmonary tissues.,
      • Function:
      • function:May be involved in cellular transformation.,PTM:N-glycosylated.,similarity:Belongs to the TDE1 family.,tissue specificity:Ubiquitous. Expression levels were increased fourfold to tenfold in lung tumor tissues compared with normal pulmonary tissues.,
      • Subcellular Location:
      • Cell membrane ; Multi-pass membrane protein . Golgi apparatus membrane ; Multi-pass membrane protein .; Cytoplasm, perinuclear region . (Microbial infection) Upon HIV-1 infection, it is redirected to perinuclear region following interaction with HIV-1 Nef, excluding it from virions particles, thereby preventing subsequent antiviral defense activity (Probable). .
      • Expression:
      • Ubiquitous. Expression levels were increased fourfold to tenfold in lung tumor tissues compared with normal pulmonary tissues.
      • Products Images
      • Western Blot analysis of various cells using TDE1 Polyclonal Antibody
      • Immunofluorescence analysis of HepG2 cells, using SERC3 Antibody. The picture on the right is blocked with the synthesized peptide.
      • Western blot analysis of lysates from 293 cells, using SERC3 Antibody. The lane on the right is blocked with the synthesized peptide.
      • Immunohistochemical analysis of paraffin-embedded human tonsil. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).