• Target：
• Wee 2

• Fields：
• >>Cell cycle;>>Human immunodeficiency virus 1 infection

• Gene Name：
• WEE2

• Protein Name：
• Wee1-like protein kinase 2

• Human Gene Id：
• 494551

• Human Swiss Prot No：
• P0C1S8

• Mouse Swiss Prot No：
• Q66JT0

• Immunogen：
• The antiserum was produced against synthesized peptide derived from human WEE2. AA range:151-200

• Specificity：
• Wee 2 Polyclonal Antibody detects endogenous levels of Wee 2 protein.

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• WB 1:500 - 1:2000. ELISA: 1:5000. Not yet tested in other applications.

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Other Name：
• WEE2;WEE1B;Wee1-like protein kinase 2;Wee1-like protein kinase 1B;Wee1B kinase

• Observed Band(KD)：
• 60kD

• Background：
• catalytic activity:ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.,function:Phosphorylates and inhibits CDC2. May act as a negative regulator of entry into mitosis (G2 to M transition).,PTM:Phosphorylated .,similarity:Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. WEE1 subfamily.,similarity:Contains 1 protein kinase domain.,tissue specificity:Expressed in testis.,

• Function：
• catalytic activity:ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.,function:Phosphorylates and inhibits CDC2. May act as a negative regulator of entry into mitosis (G2 to M transition).,PTM:Phosphorylated .,similarity:Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. WEE1 subfamily.,similarity:Contains 1 protein kinase domain.,tissue specificity:Expressed in testis.,

• Subcellular Location：
• Nucleus .

• Expression：
• Expressed in oocytes (at protein level) (PubMed:29606300). May also be expressed in testis (PubMed:11029659).

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