Kallistatin Polyclonal Antibody

    • Catalog No.:YT5216
    • Applications:WB;IHC;IF;ELISA
    • Reactivity:Human
      • Target:
      • Kallistatin
      • Gene Name:
      • SERPINA4
      • Protein Name:
      • Kallistatin
      • Human Gene Id:
      • 5267
      • Human Swiss Prot No:
      • P29622
      • Immunogen:
      • The antiserum was produced against synthesized peptide derived from the Internal region of human SERPINA4. AA range:161-210
      • Specificity:
      • Kallistatin Polyclonal Antibody detects endogenous levels of Kallistatin protein.
      • Formulation:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • Source:
      • Polyclonal, Rabbit,IgG
      • Dilution:
      • WB 1:500 - 1:2000. IHC: 1:100-300 ELISA: 1:20000.. IF 1:50-200
      • Purification:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • Concentration:
      • 1 mg/ml
      • Storage Stability:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • Other Name:
      • SERPINA4;KST;PI4;Kallistatin;Kallikrein inhibitor;Peptidase inhibitor 4;PI-4;Serpin A4
      • Observed Band(KD):
      • 47kD
      • Background:
      • function:Inhibits human amidolytic and kininogenase activities of tissue kallikrein. Inhibition is achieved by formation of an equimolar, heat- and SDS-stable complex between the inhibitor and the enzyme, and generation of a small C-terminal fragment of the inhibitor due to cleavage at the reactive site by tissue kallikrein.,miscellaneous:Heparin blocks kallistatin's complex formation with tissue kallikrein and abolishes its inhibitory effect on tissue kallikrein's activity.,PTM:The N-terminus is blocked.,similarity:Belongs to the serpin family.,subunit:Monomer and some homodimers.,tissue specificity:Expressed by the liver and secreted in plasma.,
      • Function:
      • function:Inhibits human amidolytic and kininogenase activities of tissue kallikrein. Inhibition is achieved by formation of an equimolar, heat- and SDS-stable complex between the inhibitor and the enzyme, and generation of a small C-terminal fragment of the inhibitor due to cleavage at the reactive site by tissue kallikrein.,miscellaneous:Heparin blocks kallistatin's complex formation with tissue kallikrein and abolishes its inhibitory effect on tissue kallikrein's activity.,PTM:The N-terminus is blocked.,similarity:Belongs to the serpin family.,subunit:Monomer and some homodimers.,tissue specificity:Expressed by the liver and secreted in plasma.,
      • Subcellular Location:
      • Secreted.
      • Expression:
      • Expressed by the liver and secreted in plasma.
      • Products Images
      • Western Blot analysis of K562 cells using Kallistatin Polyclonal Antibody. Secondary antibody(catalog#:RS0002) was diluted at 1:20000
      • Immunohistochemical analysis of paraffin-embedded human-colon, antibody was diluted at 1:100
      • Western blot analysis of lysate from K562 cells, using SERPINA4 Antibody.