• Target：
• GDF-3

• Fields：
• >>Cytokine-cytokine receptor interaction

• Gene Name：
• GDF3

• Protein Name：
• Growth/differentiation factor 3

• Human Gene Id：
• 9573

• Human Swiss Prot No：
• Q9NR23

• Mouse Gene Id：
• 14562

• Mouse Swiss Prot No：
• Q07104

• Immunogen：
• Synthesized peptide derived from Growth/differentiation factor 3 at AA range: 311-360

• Specificity：
• GDF-3 Polyclonal Antibody detects endogenous levels of GDF-3 protein.

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Other Name：
• GDF3;Growth/differentiation factor 3;GDF-3

• Observed Band(KD)：
• 41kD

• Background：
• This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein plays a role ocular and skeletal development. Mutations in this gene are associated with microphthalmia, coloboma, and skeletal abnormalities in human patients. [provided by RefSeq, Aug 2016],

• Function：
• online information:GDF3 entry,similarity:Belongs to the TGF-beta family.,subunit:Homodimer or heterodimer (Potential). But, in contrast to other members of this family, cannot be disulfide-linked.,

• Subcellular Location：
• Secreted . Cytoplasm . Mainly accumulated in the cytoplasm. .

• Expression：
• Kidney,

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