• Target：
• CTACK

• Fields：
• >>Cytokine-cytokine receptor interaction;>>Viral protein interaction with cytokine and cytokine receptor;>>Chemokine signaling pathway

• Gene Name：
• CCL27

• Protein Name：
• C-C motif chemokine 27

• Human Gene Id：
• 10850

• Human Swiss Prot No：
• Q9Y4X3

• Mouse Gene Id：
• 100039863

• Mouse Swiss Prot No：
• Q9Z1X0

• Immunogen：
• Synthesized peptide derived from C-C motif chemokine 27 at AA range: 51-100

• Specificity：
• CTACK Polyclonal Antibody detects endogenous levels of CTACK protein.

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• WB 1:500 - 1:2000. IHC: 1:100-1:300. ELISA: 1:10000.. IF 1:50-200

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Other Name：
• CCL27;ILC;SCYA27;C-C motif chemokine 27;CC chemokine ILC;Cutaneous T-cell-attracting chemokine;CTACK;ESkine;IL-11 R-alpha-locus chemokine;Skinkine;Small-inducible cytokine A27

• Observed Band(KD)：
• 12kD

• Background：
• This gene is one of several CC cytokine genes clustered on the p-arm of chromosome 9. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The protein encoded by this gene is chemotactic for skin-associated memory T lymphocytes. This cytokine may also play a role in mediating homing of lymphocytes to cutaneous sites. It specifically binds to chemokine receptor 10 (CCR10). Studies of a similar murine protein indicate that these protein-receptor interactions have a pivotal role in T cell-mediated skin inflammation. [provided by RefSeq, Sep 2014],

• Function：
• function:Chemotactic factor that attracts skin-associated memory T-lymphocytes. May play a role in mediating homing of lymphocytes to cutaneous sites. Binds to CCR10.,online information:CCL27 entry,similarity:Belongs to the intercrine beta (chemokine CC) family.,tissue specificity:Testis, thymus, placenta, ovary and skin.,

• Subcellular Location：
• Secreted .

• Expression：
• Testis, thymus, placenta, ovary and skin.

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