• Target：
• ULK2

• Fields：
• >>Autophagy - other;>>Autophagy - animal;>>mTOR signaling pathway;>>Alzheimer disease;>>Amyotrophic lateral sclerosis;>>Huntington disease;>>Spinocerebellar ataxia;>>Pathways of neurodegeneration - multiple diseases

• Gene Name：
• ULK2 KIAA0623

• Protein Name：
• unc-51-like kinase 2 (C. elegans)

• Human Gene Id：
• 9706

• Human Swiss Prot No：
• Q8IYT8

• Mouse Gene Id：
• 29869

• Mouse Swiss Prot No：
• Q9QY01

• Immunogen：
• Synthetic peptide from human protein at AA range: 930-1000

• Specificity：
• The antibody detects endogenous ULK2 protein

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• WB 1:500-2000, ELISA 1:10000-20000

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Other Name：
• ULK2 KIAA0623

• Observed Band(KD)：
• 140kD

• Background：
• unc-51 like autophagy activating kinase 2(ULK2) Homo sapiens This gene encodes a protein that is similar to a serine/threonine kinase in C. elegans which is involved in axonal elongation. The structure of this protein is similar to the C. elegans protein in that both proteins have an N-terminal kinase domain, a central proline/serine rich (PS) domain, and a C-terminal (C) domain. The gene is located within the Smith-Magenis syndrome region on chromosome 17. Alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq, Dec 2008],

• Function：
• catalytic activity:ATP + a protein = ADP + a phosphoprotein.,PTM:Autophosphorylated.,similarity:Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. APG1/unc-51/ULK1 subfamily.,similarity:Contains 1 protein kinase domain.,

• Subcellular Location：
• Cytoplasmic vesicle membrane ; Peripheral membrane protein . Localizes to pre-autophagosomal membrane.

• Expression：
• Brain,Testis,

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